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Use of mild therapeutic hypothermia as a part of interventional therapy of patients with cardiac arrest due to acute coronary syndrome

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Tytuł: Use of mild therapeutic hypothermia as a part of interventional therapy of patients with cardiac arrest due to acute coronary syndrome

Autor:

Trąbka-Zawicki, Aleksander

Data:

2019

Typ:

Praca doktorska

Abstrakt:

In the group of patients admitted for interventional management of acute coronary syndrome complicated with cardiac arrest, significant inhibition of platelet activity in response to ticagrelor - a novel P2Y12 receptor inhibitor - has been documented in mild therapeutic hypothermia (MTH) conditions (32-34 degrees Celsius). The degree of platelet activity inhibition in this group was similar to the control group - conscious acute coronary syndrome patients treated interventionally in normothermic condition.Clinical efficiency of dual antiplatelet therapy (DAPT), consisting of ticagrelor, a novel oral P2Y12 receptor inhibitor, in combination with acetylsalicylic acid, as a therapy supportive to PCI in MTH conditions in out-of-hospital cardiac arrest (OHCA) patients, defined as freedom from thromboembolic events, has been confirmed. However, increased numbers of severe bleeding complications was observed in this group, what required intensive care unit (ICU) monitoring and blood transfusion therapy.Further clinical course and neurological condition in this group was favourable and dependent on cardiac arrest mechanism, occurrence and timing of early cardiopulmonary resuscitation, time to return of spontaneous circulation, lack of shock and renal failure, and, independently, on e

Miejsce wydania:

Kraków

Stopień studiów:

2 - studia doktoranckie

Dyscyplina:

choroby układu krążenia

Instytucja nadająca tytuł:

Wydział Lekarski

Promotor:

Żmudka, Krzysztof

Data wydania:

2017

Identyfikator:

oai:dl.cm-uj.krakow.pl:4387

Sygnatura:

ZB-130895

Język:

pol

Prawa dostępu:

nieograniczony

Temat i słowa kluczowe:

acute coronary syndrome cardiac arrest therapeutic hypothermia

Kolekcje, do których przypisany jest obiekt:

Data ostatniej modyfikacji:

24 lis 2025

Data dodania obiektu:

13 paź 2020

Liczba wyświetleń treści obiektu:

166

Liczba wyświetleń treści obiektu w formacie PDF

28

Wszystkie dostępne wersje tego obiektu:

http://dl.bm.cm-uj.krakow.pl:8080/publication/4388

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RDF

Wyświetl opis w formacie OAI-PMH:

OAI-PMH

Nazwa wydania Data
ZB-130895 24 lis 2025

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Dane kontaktowe

Adres

Biblioteka Medyczna
ul. Medyczna 7
30-688 Kraków

Telefon

12 658 72 56
517 385 669

E-Mail

Oddział Gromadzenia i Opracowania Zbiorów
cyfrowabm@cm-uj.krakow.pl

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