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Title: Short- and long-term complications after multisystem inflammatory syndrome in children depending on individual variants of SARS-CoV-2

Author:

Ptak, Katarzyna

Date:

2025

Type:

Praca doktorska

Abstract:

The main objective of the doctoral dissertation was to assess the clinical course of MIS-C and the short- and long-term complications of the syndrome in subsequent waves of the pandemic (original/Alpha, Delta and Omicron). We assessed in detail the presentation of cardiac complications and the impact of MIS-C during subsequent waves of the pandemic on die quality of life and the incidence of long-COVID. Based on the data obtained, it was found that the clinical course of MIS-C in the first waves of the pandemic (original/Alpha and Delta) was comparable and remained a serious, life-threatening condition. A positive correlation was found between the age of patients and the occurrence of cardiac failure with systolic function impairment and/or hypotension. However, regardless of the period of the pandemic, rapid disappearance of symptoms of cardiac failure was observed, and other cardiac abnormalities resolved within a few weeks. No new cardiac abnormalities were found during the entire follow-up period. A high incidence of long-COVID symptoms after MIS-C was demonstrated in the entire study population. At the same time, in long-term follow-up based on the results of a standardized questionnaire, it was found that the quality of life of patients was not worse than that of the general population. These long-COVID symptoms are non-specific, which can lead to overdiagnosis.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

pediatria ; choroby zakaźne

Degree grantor:

Rada Dyscypliny Nauki medyczne

Promoter:

Kwinta, Przemko

Date issued:

2024

Identifier:

oai:dl.cm-uj.krakow.pl:6127

Call number:

ZB-143485

Language:

pol; eng

Access rights:

tylko w bibliotece

Subject and keywords:

multisystem inflammatory syndrome in children SARS-CoV-2 Variants of Concern long-COVID cardiac complication

Object collections:

Last modified:

Mar 30, 2026

In our library since:

Mar 20, 2026

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All available object's versions:

http://dl.bm.cm-uj.krakow.pl:8080/publication/6128

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ZB-143485 Mar 30, 2026

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